An Arc of Unpaired “Hinge Bases” Facilitates Information Exchange among Functional Centers of the Ribosome
نویسندگان
چکیده
منابع مشابه
An arc of unpaired "hinge bases" facilitates information exchange among functional centers of the ribosome.
Information must be shared and functions coordinated among the spatially distinct functional centers of the ribosome. To address these issues, a yeast-based genetic system enabling generation of stable strains expressing only mutant forms of rRNA was devised. The B1a bridge (helix 38) has been implicated in the subtle modulation of numerous ribosomal functions. Base-specific mutations were intr...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2006
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.01311-06